Eliquis hair loss forum

How Do You Know If Your Dog Has Mange?

Eliquis and hair loss. Fs13jfw •. 4 years ago • 43 Replies. Hi. I'm 25 and recently broke my hip - I was given Eliquis to take but after 6 weeks I have severe hair thinning and my hair is now falling out more quickly and eyelashes aswell eliquis, hair. After a few weeks on Eliquis I began to have noticeable hair loss (not clumps exactly, but a lot coming out when brushing or washing my hair). After a few days of this, I switched back to my previous blood thinner (Innohep), on which I had no noticeable side effects. But I'm a few days in and my hair is still coming out

Eliquis and hair loss: Hi I'm 25 and recently - AF

Hi derek 76. He had eye bleeds, hair loss, a horrible blood blister looking swelling on his back where a previous mole biopsy had been done, nasty mood swings, pains in his ankles...the list goes on. I bought a coaguchek machine as if his INR went above 2 all the above happened and the GP/clinic wouldn't see him often enough Eliquis Side Effects. Generic name: apixaban Medically reviewed by Drugs.com. Last updated on May 13, 2020. Consumer; Professional; Note: This document contains side effect information about apixaban. Some of the dosage forms listed on this page may not apply to the brand name Eliquis.. For the Consume ing). Following this change, she immediately noted less hair loss and over time had complete hair regrowth. Due to preference for an oral anticoagulant, a trial of apixaban (2.5 mg twice daily) was attempted which again resulted in rapid hair loss, resolving upon transition t

Eliquis (Apixaban) received an overall rating of 5 out of 10 stars from 134 reviews. See what others have said about Eliquis (Apixaban), including the effectiveness, ease of use and side effects decreased blood platelets. bleeding from the retina. bleeding in the eye. abnormal bleeding in the brain resulting in damage to brain tissue, called a hemorrhagic stroke. bleeding within the skull. Our Eliquis (apixaban) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 Pumpkin seed oil may reduce the effects of 5-alpha reductase, which is an enzyme that contributes to hair loss. The authors of a 2014 study. Trusted Source. looked at the effects of pumpkin seed.

New Eliquis (Apixaban) Alert: Unexpected Side Effect. A few years ago we received alerts about an increasing number of serious bleeding episodes associated with the anticoagulant Eliquis (Apixaban). This medication is prescribed to prevent blood clots in patients with an irregular heart rhythm called atrial fibrillation (AFib). The drug is also. Find 113 user ratings and reviews for Eliquis Oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfactio Summary: Hair loss is found among people who take drugs with ingredients of apixaban, especially for people who are female, 60+ old , have been taking the drugs for 1 - 6 months.This phase IV clinical study is created by eHealthMe based on reports of 116,932 people who have side effects when taking drugs with ingredients of apixaban from the FDA, and is updated regularly Hair loss is associated with the anticoagulants heparin and warfarin. With the recent availability of direct oral anticoagulants (DOACs) it is of clinical interest to know if they are implicated with hair loss and/or whether they could be successfully prescribed for patients who suffer from coumarin- or heparin-related alopecia

Stopping Eliquis due to hair loss - when will I see

  1. Hair loss is not a known side effect of the NOACs rivaroxaban, dabigatran or apixaban. However, it is known to occur with the anticoagulants heparin and warfarin. The exact mechanism for hair loss with heparin and warfarin is unknown but is thought to occur through telogen effluvium
  2. Some people report hair loss when taking certain anticoagulants. Apixaban does not seem to affect the hair or cause hair loss. But if you have any concerns about your hair while taking this medicine or you notice any changes, speak to your doctor or pharmacist
  3. The bottom line is, if you are experiencing hair loss - or hair thinning - to any extent, it can be devastating to your self-esteem during what is already a difficult recovery from blood clots. No matter what the cause might be, I am going to share my top tips to help fix your thinning hair. I have naturally thin and straight hair
  4. Hair loss is a side effect of certain medications. Read on to find out which medications can cause hair loss. We also provide tips on how to prevent and reverse hair loss
  5. Minor side effects such as hair loss and dry skin associated with Xarelto can ruin a patient's quality of life even if they're not included on the medication's label. Everybody cares about its appearance, and many doctors and patients are complaining about these uncommon adverse reactions that Bayer never warned the public about

Decided to stop apixaban 2 days ago. Aches and joint pains subsiding. It's early days yet but it appears as if apixaban causes muscle and joint pain. G.P.'s appear to be fixated on The National Formulary information on drugs. Printed outdated ,and only contains information supplied by the drug makers. Say no more Hair loss in relation to Xarelto is most common in females that are over the age of 60, have been taking the drug for about one to six months, also take Vitamin D, and have Atrial fibrillation. Patients taking Xarelto that experienced hair loss also reported multiple sclerosis, rheumatoid arthritis, high blood pressure, hepatitis c, and depression Eliquis Side Effects. Eliquis and similar anticoagulants can cause side effects, both mild and severe. Although not frequent, fatigue, nausea and other minor effects have been reported. People taking Eliquis have also reported severe bleeding and liver damage. The blood thinner has also been linked to blood clots and an increased risk of stroke. ELIQUIS (ELL eh kwiss) blood clot that can cause long-term or permanent loss of the ability to move (paralysis). Your risk of developing a spinal or epidural blood clot is higher if

DIY Protein Mask for Reducing Hair Loss, Dandruff | Get

Yes hair loss is a potential side effect. Detailed Answer: Hi, Thank you for posting your query in healthcaremagic.com. This is Dr. Swarnava dattagupta answering your query. Though there are not any proved data of apixaban causing hair loss, still from many papers and clinical practice, I might say that yes, new onset hair loss is a potential. I was given Eliquis 5 mg and dilitazen and then metoprolol. Metoprolol had more severe side effects ; more pain in my joints, heavy loss of hair, feeling tired all the time and lack of apetite. So I stopped ( first reduce led the sizes and then stopped) for last one and a half month I am taking only Eliquis Hair loss is associated with the anticoagulants heparin and warfarin. With the recent availability of direct oral anticoagulants (DOACs) it is of clinical interest to know if they are implicated with hair loss and/or whether they could be successfully prescribed for patients who suffer from coumarin- or heparin-related alopecia. Initially reports of heparin- and coumarin-associated alopecia. Brief Report: Hair Loss Linked to Dopamine Agonists. It is foolish to pluck out one's hair for sorrow, as if grief could be assuaged by baldness.. Marcus Tullius Cicero. Anyone can be confident with a full head of hair. But a confident bald man - there's your diamond in the rough.. Larry David

I thought I was menopausal from March 18 as haven't had a period for 6 months and am definitely not pregnant, symptoms of menopause were bad, confused at little things, blotting, hair loss, hot sweats half a month on blood thinners and my period came back, really concerned I will now have periods and menopausal symptoms on top of kidney issues Hair loss is a common side effect of many medications. Most of the time, these drugs only cause temporary hair loss that goes away once you've adjusted to or stopped taking the medicine Following episodes of AFib post cardiaC Sx I was on Warfarin for years. Then @ 86 yrs I was in an accident resulting in much blood loss. While still hospitalized I was placed on Xarelto and then Eliquis, both causing many bad side effects. The Eliquis, which I still take, has caused vertigo, joint pain, and a very bad rash on my torso Eliquis is mostly used to prevent blood clots for people who have had a total hip replacement or knee replacement surgery, for the prevention of venous thromboembolism (blood clots in the veins) and the prevention of stroke in atrial fibrillation. 2.) The drug prevents clot formation by blocking an important pathway It is thought to cause hair loss by inducing hypothyroidism by blocking conversion of T4 to T3, the more active form of thyroxine. However, there have been studies suggesting that certain drugs, including beta-blockers, may induce alopecia. WebMD and The Mayo Clinic list hair thinning as a rare side effect of metoprolol

Hair loss,fatigue,abdominal weight gain, tinnitus: Dreadful drug: M: 75 6 years: 8mg 1X D 11/17/2020: 5: Hypertension: None: F: 78 20 years: 32 mg 4/25/2020: 1: BP I have been taking 4mg Atacand for around 18 months along with 5mg Amlodipine taken at the same time of day If you need to stop taking Eliquis, ask your doctor first, since changing your medication could be dangerous. If you experience side effects like bloody urine or feces, chest pain, dizziness, swelling in your face, or if you have a stroke, stop taking Eliquis and go to the hospital immediately. Then, consult your doctor loss of appetite or weight loss metallic taste skin rash or itching sleepiness spinning or whirling sensation causing loss of balance stomach pain or upset trouble sleeping vomiting weakness Incidence not known. Bad, unusual, or unpleasant (after) taste and thirst being forgetful change in taste dryness of the skin hair loss

Eliquis - Blogs & Forum

I used Eliquis at Doctors request but began having blood in my urine. Changed to Xerelto with advice from another doctor, and the same symptoms appeared. I stop taking the pill and the blood clears up quickly and each time I restart taking the blood thinner pill, usually the next day, blood reoccurs within a couple of hours 51 years old. Have AFIB (about every 3-4 months now for short periods of time (under 8 hours each time)). CHADs score of 2 (diabetes and hypertension). Cardiologist suggesting Eliquis. I am very concerned about everything I read regarding the side effects of Eliquis (bleeding, joint pains, fatigue, hair loss, etc.) In the U.S., 1.3 percent of adults use CoQ10 supplements, and that rate has increased since 2007, according to National Center for Complementary and Integrative Health (NIH). NIH also reports that, although mild, a range of CoQ10 side effects are possible. Whether taking CoQ10 as a tablet, capsule or by injection into a vein, be aware of the following side effects reported by National Cancer. Hair Loss. Hair loss is a relatively common side-effect of warfarin, which can be especially distressing to women. It can occur at any time although it is more common soon after starting warfarin. It is usually noticed as thinning of the hair rather than loss of large clumps of hair and total baldness has never been reported with warfarin The study recommended that physicians treating male pattern hair loss (MPHL) should discuss the potential risk levels with patients while prescribing the drug. An important earlier study by Mella et al ,[ 14 ] conducted a systematic review of twelve randomized trials evaluated the efficacy and safety of finasteride therapy in 3927 male patients

Coronavirus survivor suffers devastating hair loss as

21 May 2018. I started on10mgx1 per day then increased to 1x10mg twice per day as BP was not controlled. Had to go back to 1x10mg per day as side effects were intolerable. (swollen, hard, red, hot lower legs and feet , worse late evening and disturbance of sleep. Also I have itchy rash on my back These worths are similar to those acquired recently in adults. A minimum of 24 hours must pass between both dosages of online pharmacy. Inform your doctor if you are taking any one of the following medicine hair loss or thinning of the hair. itching skin. muscle aching or cramping. muscle pains or stiffness. quick to react or overreact emotionally. sensation of spinning. severe sunburn. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional I've been taking MSM for about a year (2000mg in the morning, 2000mg at night). It's definitely thickened my hair shafts as well as sped up the growth rate. One big question: Does MSM thin the blood? My HT is on May 20th with Dr. Arocha, and I certainly don't want to make his job more difficult b..

Using biotin for hair loss is typically affordable and is all natural. While some dermatologists believe 1 to 2 milligrams of biotin is the minimum requirement for healthy hair, the recommended daily intake for healthy people is 30 to 100 micrograms. People suffering from hair loss due to an insufficiency of biotin usually require 3 to 5 mg daily Hair Loss GetHealthyStayHealthy. Some patients notice hair loss while taking blood thinners. Although this is not considered a serious side effect, it can be distressing for the patient. Patients might find their hair comes out more easily or in larger clumps when brushed, and the use of heated styling devices, hairspray, and hair gels could. But 2019 guidelines recommend newer blood thinners known as non-vitamin K oral anticoagulants (NOACs) or direct-acting oral anticoagulants (DOACs), such as apixaban (Eliquis), dabigatran (Pradaxa. Blood-thinning drugs, like the anticoagulants used to treat Hillary Clinton, are a medicinal cash cow for the pharmaceutical industry. A new one was just approved by federal regulators - Eliquis, made by Bristol-Myers Squibb - and it is expected to be a money-making blockbuster

Hi Boymook, welcome to the forum .Hair thinning seems pretty common Im afraid ,my hair thinned significantly on Tamoxifen -hairline receded and thinned at the sides noticeably .Some ladies have tried biotin supplements to help ,others have been prescribed Regaine for women by doctor ,did you discuss the hair loss at your review? Jill The sources of her hair loss actually started much earlier. Though there were stints when her hair was fine, the shedding always came back. Ricki says the cause of her hair loss over the years has. Butea superba is a shrub native to Thailand, India, and Vietnam that is believed to have aphrodisiac properties. Used in traditional Thai medicine, the roots of Butea superba contain compounds said to improve sexual performance, treat erectile dysfunction, and even boost sperm counts. In scientific studies, Butea superba 's roots have been. An anticoagulant drug, Xarelto is a prescription medication designed to prevent blood clots from forming by thinning the blood in patients suffering from atrial fibrillation and pulmonary embolism (PE) as well as those recovering from hip or knee replacement surgery. It also helps to prevent and treat deep vein thrombosis (DVT). It is also known by its generic name, rivaroxaban

New-generation anticoagulants such as rivaroxaban (Xarelto) and apixaban (Eliquis) carry a risk of bleeding under the best of conditions. If a patient requires emergency surgery, the possibility. Uncommon Side Effects of Eliquis: Bleeding in the nose, gums, eyes, rectum, hemorrhoids, urine, etc. Allergic reactions (rash) Fainting or loss of consciousness; Xarelto Side effects: Bleeding (this is the most serious adverse reaction and can be life threatening; platelets can be decreased) Itching (skin rash), other allergic reaction Like saw palmetto, it stimulates certain processes in men to end the long-standing problem of hair loss and thinning. Modern studies suggest that this is thanks to the compound known as procyanidin B2, an antioxidant found in Butea Superba, apples, grapes, and other fruits as well

The hair loss is what prompted me to write this, but memory is a concern too. I know NP and many NDTs have been reported to be bad now, but I am terrified to go back on Synthroid. It took me 9 years after switching to NDTs to lose 45 lbs and feel better 4) Antioxidant Effects. In animals and test tubes, calcium-d-glucarate protected blood components (such as platelets) from chemical damage. It may act as an antioxidant, protecting cells from free radicals [45, 46].In one animal study, the active form of calcium-D-glucarate prevented organ damage in diabetic rats [].Purported Benefits With No Evidenc Hair Loss and Acne Claims. The effects of pygeum extract on hair loss and acne prevention have not been clinically tested and are speculations based on its anti-male sex hormone activity [44, 16, 15]. Side Effects & Precautions. Keep in mind that the safety profile of pygeum extract is relatively unknown, given the lack of well-designed.

Hi Helan, 30 mcg is the recommended dosage for your age. However, it is normally safe even in higher dosages. Some users have reported acne break outs as one the side effects of biotin. Hair on various parts of body is regulated by hormones. If you already have facial hair then there are chances that biotin will encourage more hair growth Hair loss that occurs when taking Coumadin is reversible, and the hair will grow back once the treatment is discontinued. Mild hair loss is relatively common when taking Coumadin, while severe hair loss is less common. Complete hair loss has not been reported as a side effect of the drug

12 Home Recipes With Fenugreek (Methi) Seeds For Hair Growth

Eliquis and Hair Loss -- a Connection? - AF Associatio

The loss of calcium in the urine increases bone loss and fracture risk. In contrast, thiazide diuretics cause the kidney to hold on to calcium, and tend to increase bone density. There is also research that connects the use of some loop diuretics with falls and increases the risk of spine fractures. To lessen the harm to the bones from loop. benign prostatic hypertrophy, or BPH. inflammation. erectile dysfunction. kidney disease. male baldness. stomach upset. urinary tract disorders. Pygeum is also purported to act as a natural aphrodisiac, enhance sexual performance, and protect against prostate cancer 2 Tips For Female Hair Loss In Late 30s. 2.1 Does Milk Cause Hair Loss Vitamins For Hair Loss While Breastfeeding. 3 Encourage Horse Hair Regrowth Dies Hair Loss From Pos Grow Back. 3.1 Acne And Hair Loss Can Result From. 3.2 Hair Loss Protocol Torrent Hair Loss And Darkened Skin On Arodesian Rigeback

Eliquis Forums - MedsCha

Hair loss, fatigue, and a swollen tongue can all be symptoms of low iron levels. By Ashley Welch October 25, 2017. A Guide to Anemia Symptoms. From fatigue to arrhythmia, anemia causes a wide. What Is Crestor? Crestor (rosuvastatin calcium) is a statin drug, that works by slowing the production of cholesterol by the body, used to lower cholesterol and fats (triglycerides) in the blood and is used to reduce the chances of developing problems like heart disease and strokes that can be caused, in part, by high cholesterol levels. It is often recommended to use Crestor in conjunction.

Hair loss, on Xarelto - Blood clots - Inspir

Amiodarone (Cordarone) is considered one of the most effective antiarrhythmic drugs, but it's also one of the most toxic. It may affect your lungs, eyes, thyroid, liver, skin, heart, and nervous system. Also, amiodarone has a long half-life. It is retained in the body for up to 45 days after the drug has been discontinued 5. You also want to reduce inflammation. The ginger extract does a great job of this, while also inhibiting platelet aggregation - which means, it reduces the clumping of blood. And for more specific details on how each of these ingredients works, the exact type, extract, and dosage, you can read about it here

Hair loss in Eliquis: how severe and when it was recovered

But if you're on a newer anticoagulant — like Pradaxa or the factor Xa inhibitors Xarelto (rivaroxaban), Eliquis , and Savaysa (edoxaban) — vitamin K levels won't interfere with effectiveness Valsartan is a high blood pressure drug that is considered generally safe and tolerated better by patients than alternative treatments. Like any drug, however, it comes with side effects.. Some side effects of the blood pressure medication are more serious than others and require medical attention. Possible serious side effects include allergic reactions and rare instances of liver damage Evoltuion Hair Loss Instotute Wash And Go Hair Loss Loss Of Hair Teenage Girl 29 Year Old Female Hair Loss Do You Alwaya Loose Your Hair With Weight Loss Surgery. Can Hair Loss Be Reversed After Arthritis Medication Does Protein Hair Treatment Cause Hair Loss Jimmy Tatro Hair Loss Peri Menopauce And Hair Loss Brilinta 9 0mg online in india. SARM1 programs brilinta 9 0mg online in india difference between plavix and brilinta for COVID-19. The intended users of the disease. Numerous cases of brilinta 9 0mg online in india notifiable diseases reported for 2010. COVID-19 risk in Papua New Guinea. This document provides guidance to assist the diverse needs of people with intellectual disabilities

I am experiencing hair loss

Letrozole. 23 Oct 2017 07:24. Hi I'm new to this forum. I have had breast cancer twice, 2nd time round was in the same breast. Because of this I decided to go for a double mastectomy to avoid a 3rd time. First time round I was put into Tamoxifen for 5 years, apart from the common side effect of hot flushes & mega weight gain I felt well. Hair loss isn't something I commonly see with the newer blood thinners. I have occasionally seen it as well with amiodarone but much less commonly with other antiarrhythmics like flecainide. In general, once the offending drug is removed, the hair slowly comes back

ELIQUIS: Side Effects, Reviews by Patients - AskaPatient

Worsening hair loss or hair thinning If you experience any of these side effects you should see your physician as soon as possible to have your blood drawn and to potentially reduce your dose. Excessively high doses of thyroid hormone may put you at risk for a condition known as thyrotoxicosis Report. Hi misspc. I was on Otezla for 3 months. I had to get off of it because I had so many bad side effects. (tension headache, depressed and terrible knee joint pain). I was on it for guttate P. Now that I am off of it I feel so much better. I am not depressed, no tension headache or diarrhea

Nov 28, 2008. #1. My girlfriend has been on Dilantin and then Phenobarbital with success for many years. Currently on Phenobarbital for the past 10 plus years. Last Grand Mal seizure around 7 years ago. However, it doesn't seem to be as effective as it has been and she is looking for an alternative drug with less side effects (sedation. Hair loss (alopecia) is a relatively common condition, according to the American Academy of Dermatology. Short-term conditions, such as pregnancy, may cause temporary hair loss. But long-term hair. I have a fear of Eliquis and Warfarin, pushed by all my doctors Heparin too was prescribed for a few days have not picked anything up yet I have started nattokinase 100mg 2x/day for the last two days, and serrapeptase up to 100,000SU for the same time I also have been using topical DMSO on the leg, 2x/day 60% gel and mag oil

License: Except as otherwise noted, this work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.For commercial use or customized versions, please contact biobyte solutions GmbH.. Disclaimer: The content of this database of side effects (adverse drug reactions) is intended for educational and scientific research purposes only A common consequence faced by individuals who use blood thinner is the excessive release of blood. Since the blood thinner interferes with the blood ability to clot together, it's ability to regulate the flow is hampered. This essentially means that the slightest cut or injury can lead to excessive amount of blood loss from the body 1) Eating too much gelatin or collagen and/or using the wrong kind for you can cause digestive upset —> constipation, bloating and lack of appetite. The primary amino acid in gelatin and collagen is glycine, and it is needed in abundance to fuel detoxification in the liver, particularly phase 2. According to Peter Bennet in The 7 Day Detox. Healthline has Cbd Interaction With Eliquis strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy

Apixaban Side Effects? Anticoagulants Forums Patien

Day-to-day movements, like washing hair, putting on jerseys, or sleeping in positions that don't cause more shoulder pain, may strain the neck. Over time, the neck may become stiff or painful. Regular stretching and massage can help relieve neck tension. See Frozen Shoulder Symptoms. 3. You should use your affected ar Advise patients of signs and symptoms of blood loss and to report them immediately or go to an emergency room. Discontinue ELIQUIS in patients with active pathological hemorrhage. The anticoagulant effect of apixaban can be expected to persist for at least 24 hours after the last dose (i.e., about two half-lives) Editorial Note: This extraordinary post from Spiros might help explain the very similar problems that follow SSRIs, Finasteride, and Isotretinoin. There have been several other reports to RxISK of comparable problems on rivaroxaban - Xarelto. This drug causes many more problems than the sexual one described here. We would be interested to hear from anyone [

Eliquis Side Effects: Common, Severe, Long Term - Drugs

Tosi A, Misciali C, Piraccini BM, Peluso AM, Bardazzi F. Drug-induced hair loss and hair growth. Incidence, management and avoidance. Drug Saf 1994;10:310-317. Rivaroxaban, dabigatran and apixaban and possible risk of hair loss (alopecia) added to the medicines monitoring scheme. Medsafe New Zealand Safety Information 30 May 2016. On DermNet NZ. Blood clots can be a common - and even deadly - side effect of both cancer and its treatment. Fred Hutch's Dr. Gary Lyman, an expert in blood clots (also known as thrombi) is helping set national policy on how blood clots can be prevented in order to reduce medical costs and save patient lives

Low Ferritin, Hair Loss and Hypothyroidism Explained - YouTubeCat Hair Loss Its Causes And TreatmentHAIR LOSS TATTOO Testimonial - MARCUS - YouTubeRemedies for Cat Losing Hair | ThriftyFunRemedies for Hair Loss in Dogs | ThriftyFun

The choline-inositol-lecithin connection is unique in that it works both ways when it comes to production: the body uses choline and inositol to synthesize lecithin, but it can also operate in reverse, metabolizing choline from lecithin. Because choline is the precursor for the neurotransmitter acetylcholine, sometimes referred to as the. Confusion, loss of consciousness, depression, loss of the ability to speak, slurred speech, loss of vision, nervousness, shakiness, seizures, or changes in sleep patterns including nightmares Cool or cold skin, sweats, flushed or dry skin, sudden weakness of the body on only one side, unusual bleeding or bruising, yellow tint to the eyes or. Weight gain, hair loss, temp loss of vision, mood swings, reoccurring UTI and Yeast infections, Stroke, seizures, inter cranial pressure. They never told us non was the information available to the public as it is now! Depo is Dangerous. I have a group of over 600 women hurt by Depo and found over 240 deaths related to it that the News doesn. Eliquis (apixaban) is an anticoagulant (blood thinner) used for reducing the risk of blood clots in the heart and strokes in patients with atrial fibrillation who have no problems with their heart valves (nonvalvular atrial fibrillation).Eliquis is also used to treat and prevent deep vein thrombosis and pulmonary embolism (PE) in patients who have undergone hip or knee replacement surgery