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Rh incompatibility in pregnancy

Rh incompatibility is a condition that occurs during pregnancy if a woman has Rh-negative blood and her baby has Rh-positive blood. Learn more about causes, risk factors, screening and prevention, signs and symptoms, complications, diagnoses, treatments, and how to participate in clinical trials Rh incompatibility occurs when a pregnant woman whose blood type is Rh-negative is exposed to Rh-positive blood from her fetus, leading to the mother's development of Rh antibodies Rh incompatibility usually isn't a problem if it's the mother's first pregnancy. That's because the baby's blood does not normally enter the mother's circulatory system during the pregnancy. During the birth, though, the mother's and baby's blood can mix. If this happens, the mother's body recognizes the Rh protein as a foreign substance Rh incompatibility occurs when a pregnant woman whose blood type is Rh-negative is exposed to Rh-positive blood from her fetus, leading to the mother s development of Rh antibodies. These antibodies have the potential to cross the placenta and attach to fetal red blood cells, resulting in hemolysis, or destruction of the fetus 's red blood cells

Rh Incompatibility NHLBI, NI

Rh Incompatibility in Pregnancy The Embryo Project

Rh incompatibility is a condition that develops when a pregnant woman has Rh-negative blood and the baby in her womb has Rh-positive blood Second pregnancy: Rh incompatibility will occur during the second pregnancy IF the child again is Rh-positive (this won't be an issue if the child is Rh-negative). There is a high probability of this happening if an Rh-positive father and Rh-negative mother have another child. Pathophysiology of how Rh Incompatibility Affects the Bab

Rh Incompatibility During Pregnancy (for Parents

  1. Rh incompatibility rarely causes complications in a first pregnancy and does not affect the health of the mother. But if Rh antibodies develop, they could be dangerous to a fetus during later pregnancies. Rh disease can cause severe anemia, jaundice, brain damage, and heart failure in a newborn
  2. Rh incompatibility occurs when an Rh-negative mother carries a fetus with an Rh-positive blood type. The father of the child must either be homozygous or heterozygous Rh-positive
  3. RH Incompatibility During Pregnancy. Many of us have heard about Rh factor, but few people know what it actually is. That is not surprising, because Rh factor is a not something we deal with in everyday life. As soon as a couple start planning the pregnancy however, their incompatible Rh factors can form the Rh conflict
  4. Having an Rh negative blood type is not an illness and usually does not affect your health. However, it can affect your pregnancy. Your pregnancy needs special care if you're Rh negative and your baby is Rh positive (Rh incompatibility). A baby can inherit the Rh factor from either parent
  5. ant Rh factor gene, which in the case of an Rh-negative mother and an Rh-positive father the likelihood is about 50% or greater

Rh Incompatibility in Pregnancy - Arizona State Universit

Rh Incompatibility During Pregnancy . One of the first tests a pregnant woman should expect is a blood-type test. This test checks her blood type and Rh factor. Her Rh factor may play a role in her baby's health, so it's important to know this information early in pregnancy How Is Rh Incompatibility Treated? If a pregnant woman has the potential to develop Rh incompatibility, doctors give her a series of two Rh immune-globulin shots during her first pregnancy. She'll get: the first shot around the 28th week of pregnancy; the second shot within 72 hours of giving birt Image 1 to 4 Shows pathogenesis of rh incompatibility. There are two main mechanisms of an RH incompatibility: The most common type is an Rh-negative pregnant woman being exposed with Rh- positive fetal RBCs secondary to a case of fetomaternal hemorrhage during pregnancy as a result of abortion or any type of traum Rh Incompatibility in Pregnancy The most common type of Rh incompatibility occurs when an Rh-negative pregnant mother is exposed to Rh-positive fetal red blood cells secondary to fetomaternal hemorrhage during the course of pregnancy from spontaneous or induced abortion, trauma, invasive obstetric procedures, or normal delivery

All About Rh Incompatibility. It is a medical condition that happens over the course of pregnancy. Rh incompatibility happens if the pregnant woman is Rh-negative blood type (RBC without Rh factor) and the blood type of her unborn baby is Rh-positive (RBC with Rh factor) DEFINITION: •Rh incompatibility is a condition which develops when there is a difference in Rh blood type between that of the pregnant mother (Rh negative) and that of the fetus (Rh positive) 9 Rh incompatibility happens when an Rh-negative mother carries an Rh-positive baby. Learn more about how the condition could affect your pregnancy

Rh incompatibility in pregnancy nursing NCLEX maternity review: management, pathophysiology, Rhogam shot, and hemolytic disease of the newborn.What is Rh inc.. Rh Incompatibility During Pregnancy. Content. One of the first tests a pregnant woman should expect is a blood-type test. This test checks her blood type and Rh factor. Her Rh factor may play a role in her baby's health, so it's important to know this information early in pregnancy Learn The Facts About Rh Incompatibility. Diagnosis and Treatmen Rh incompatibility occurs when a pregnant woman has Rh-negative blood and the fetus has Rh-positive blood. Rh incompatibility can result in destruction of the fetus's red blood cells, sometimes causing anemia that can be severe. The fetus is checked periodically for evidence of anemia. If anemia is suspected, the fetus is given blood. Rh Incompatibility During Pregnancy. en español La incompatibilidad de Rh durante el embarazo. One of the first tests a pregnant woman should expect is a blood-type test. This test checks her blood type and Rh factor. Her Rh factor may play a role in her baby's health, so it's important to know this information early in pregnancy

The USPSTF recommends repeated Rh(D) antibody testing for all unsensitized Rh(D)-negative women at 24 to 28 weeks' gestation, unless the biologic father is known to be Rh(D) negative Rh incompatibility happens when an expecting mom is Rh negative and her baby is Rh positive. If your baby's blood comes into contact with yours during pregnancy or delivery, your body can build antibodies against the Rh factor Severe cases of Rh incompatibility can lead to hydrops fetalis. Immune hydrops fetalis is much less common today since the invention of a medication known as Rh immunoglobulin (RhoGAM) During the second pregnancy of an Rh- mother whose first child was Rh+, what occurs to the second fetus? Fetal Rh+ is attacked by maternal Rh antigens Maternal antibodies are formed to attack the Rh antigen in the first pregnancy, but these antibodies cannot cross the placenta Rh incompatibility during pregnancy isn't necessarily a problem during a first pregnancy. However, complications can arise in subsequent pregnancies. Last update: 06 October, 2019. The Rhesus factor was discovered in the year 1940 in the midst of an experimental study of apes

Rh Incompatibility - Women's Health Issues - MSD Manual

If you're Rh-negative and your baby is Rh-positive, your body will react to the baby's blood as a foreign substance. It will create antibodies (proteins) against the baby's blood. These antibodies usually don't cause problems during a first pregnancy. But Rh incompatibility may cause problems in later pregnancies, if the baby is Rh-positive Rh incompatibility means when a mother with RH negative blood type bears an RH positive baby. And Rh Sensitization means when the mother produces an antibody against Rh antigen. Erythroblastosis fetalis and so on. RH sensitization mostly occurs during pregnancy if RH negative woman bearing RH positive fetus Rh factor is a type of protein on the surface of red blood cells. When present, a persons blood type is Rh-positive (such as A+ or O+). When the Rh protein is absent, the blood type is Rh-negative (such as AB- or B-). Most people are Rh-positive and, in general, your Rh factor does not impact your life unless you need blood or are pregnant Once Rh incompatibility is known or suspected, medical professionals should administer additional tests for Rh antibodies later in pregnancy. The likelihood that a fetus is suffering from hemolytic anemia due to Rh incompatibility can also be estimated through the results of an amniocentesis or antibody test (1) Rh incompatibility is not an issue to be taken lightly, and Rh sensitization is a serious condition which adds layer upon layer of complication to pregnancy. The consequences of sensitization are not discussed thoroughly in any book I've ever read

Rhesus (Rh) Factor: Incompatibility, Complications & Pregnanc

Rh incompatibility is a common medical condition mostly experienced by expectant women. Rh incompatibility does not affect a person's health condition, but it can rise to problems during pregnancy. Rh incompatibility condition has been a major condition suffered by most pregnant women worldwide during their pregnancy period Buck's County Prenatal Care, Rh Incompatibility. Doylestown Women's Health Center is your Bucks County OB GYN, and a comprehensive resource for topics in women's health. Our patients come from all walks of life, and everyone's journey is unique. If your journey includes pregnancy, our mission is to support you and your baby, even through. Rh incompatibility is a condition that develops when a pregnant woman has Rh-negative blood and the baby in her womb has Rh-positive blood. Causes. During pregnancy, red blood cells from the unborn baby can cross into the mother's blood through the placenta. If the mother is Rh-negative, her immune system treats Rh-positive fetal cells as if. Sensitization to an antigen occurs when the immune system encounters an antigen for the first time and mounts an immune response. In the case of HDN caused by Rh incompatibility, an Rh D-negative mother may first encounter the D antigen while being pregnant with an Rh D-positive child, or by receiving a blood transfusion of Rh D-positive blood With Rh incompatibility, if some of the fetal blood gets into your bloodstream, your body will produce antibodies. These antibodies could pass back through the placenta and harm the developing baby's red blood cells, causing very mild to very serious anemia in the fetus. Your first baby is usually safe, because fetal and maternal blood usually.

Rh Incompatibility. Rh incompatibility is a mismatched blood type between a pregnant mother and the baby she is carrying. It once was a serious medical problem for the baby. Today, Rh incompatibility rarely is serious or life threatening, thanks to early diagnosis and treatment during pregnancy. Rh factor is a protein located in red blood cells Rh incompatibility is when a mom is Rh negative and her baby is Rh positive, which can cause problems during pregnancy. If the baby's Rh positive blood cells enter the mother's circulation, her immune system may view them as foreign — and, in a normal immune response, mobilize armies of antibodies to attack these unfamiliar cells

The Rh Factor: How It Can Affect Your Pregnancy ACO

  1. If a pregnant woman has the potential to develop Rh incompatibility, doctors give her a series of two Rh immune-globulin shots during her first pregnancy. She'll get: the first shot around the 28th week of pregnancy. the second shot within 72 hours of giving birth. Rh immune-globulin acts like a vaccine. It prevents the mother's body from.
  2. e your blood type and Rh factor. You are either Rh-positive (as approximately 85 percent of Caucasians and a slightly higher percentage of African Americans and Asians are) or you are Rh.
  3. Rh incompatibility can be prevented with an injection of Rh immune globulin at week 28 of the pregnancy. A second injection will be given within 72 hours after delivery. The injections will block the mother's body from developing antibodies
  4. Rh incompatibility signs and symptoms. Expectant mothers who are pregnant for the first time don't typically have issues with Rh sensitivity and incompatibility. After the first pregnancy, however, an Rh-negative mother becomes sensitized to an Rh-positive baby. Some of the symptoms of Rh incompatibility in a baby include
Immense Immunology Insight: Rh incompatibility

Rh Incompatibility: Symptoms, Diagnosis & Treatment

  1. How often should pregnant women with red cell antibodies who are at high risk of requiring a transfusion (placenta praevia, sickle cell disease etc.) be tested? Pregnant women with red cell antibodies, who are assessed as being at high risk of requiring a blood transfusion, should have a cross-match sample taken at least every week
  2. ABO incompatibility occurs too, but it is usually not as severe as Rh incompatibility, for a couple reasons: There is a low density of ABO antigens on fetal red cells. Serum soluble A and B antigens in the fetus neutralize anti-A and anti-B antibodies. Anti-A and anti-B antibodies are naturally-occurring, by the way (you don't have to be.
  3. Rh incompatibility is a condition that happens when an Rh-negative woman is exposed to an Rh-positive blood. It usually occurs either during pregnancy or blood transfusion. Being Rh-positive means that one's red blood cells contain a protein, called an Rh-factor.Conversely, being Rh-negative means that the Rh factor is absent
  4. Isoimmunization (Sometimes called Rh sensitization, hemolytic disease of the fetus, Rh incompatibility) What is isoimmunization? A condition that happens when a pregnant woman's blood protein is incompatible with the baby's, causing her immune system to react and destroy the baby's blood cells
  5. Rh incompatibility usually isn't a problem if it's the mother's first pregnancy because, unless there's some sort of abnormality, the fetus's blood does not normally enter the mother's circulatory system during the course of the pregnancy

Rh-Factor Blood Type and Pregnancy American Pregnancy

If a mother has the potential to have Rh incompatibility during pregnancy, prophylactic RhIg should be administered to unsensitized Rh-negative women at 28 weeks gestation. If the neonate is found to be Rh-positive after delivery, those same unsensitized Rh-negative women should be given RhIg within 72 hours of delivery.. The U.S. Preventive Services Task Force (USPSTF) last addressed screening for Rh(D) incompatibility in the 1996 Guide to Clinical Preventive Services and recommended Rh(D) blood typing and antibody screening for all pregnant women at their first prenatal visit (A Recommendation). The USPSTF also recommended repeat antibody screening at 24 to 28 weeks' gestation for unsensitized Rh(D)-negative. The protective effect of ABO incompatibility between mother and fetus in respect of pregnancy-induced Rh isoimmunization has been recognized for approximately 20 years. Many have tacitly assumed that this protection was absolute and that when an infant was born with Rh hemolytic disease of the newbo Rh incompatibility can harm a second (or later) pregnancy. If you have Rh antibodies from an earlier pregnancy, now your Rh-positive baby could have problems. Your Rh antibodies may destroy some of your baby's red blood cells and cause your baby to have Rh incompatibility occurs during pregnancy if the mother is Rh- and the baby is Rh+. This is problematic because the mother's body does not recognize the Rh protein and will treat it as a foreign substance. This occurs because the blood typing proteins are antigens, which attract immune system antibodies..

The Coombs' Test Newborn Nursery Stanford Medicin

  1. Rh disease (also known as rhesus isoimmunization, Rh (D) disease) is a type of hemolytic disease of the fetus and newborn (HDFN). HDFN due to anti-D antibodies is the proper and currently used name for this disease as the Rh blood group system actually has more than 50 antigens and not only D-antigen
  2. Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/medicosis/ - With Picmonic, get your life back by studying less and remembering more. Med..
  3. e your blood type and Rh status
  4. Rh negative mother, Rh positive fetus - 1'st pregnancy is always unaffected Give Rhogam at 28 weeks, within 72 hours of delivery and during any uterine bleeding throughout pregnancy. Given if Rh negative mother and father Rh positive or unknown. Risk of hydrops fetali
  5. Isoimmunization from non-abo, non-rh blood-group incompatibility affecting pregnancy Isoimmunization irregular blood group incompatibility ICD-10-CM O36.1990 is grouped within Diagnostic Related Group(s) (MS-DRG v 38.0)
  6. Rh incompatibility during pregnancy can sound like a scary thing, and gone untreated it can be dangerous to you and your baby. This post is intended to cover all the facts about Rh incompatibility and how to prevent any potential problems

If Rh-positive blood enters the bloodstream of a person with Rh-negative blood, the immune system will recognize the Rh-positive blood as a foreign substance and begin making antibodies to fight against it. This is referred to as Rh incompatibility or Rh disease. First-time pregnancies are usually unaffected by Rh incompatibility RH factor is a protein on some people's red blood cells. RH disease, or RH incompatibility, occurs when an RH-negative mother is pregnant with an RH-positive baby. Learn how RH disease affects your baby and how to prevent it

Rh incompatibility isn't usually a problem during your first pregnancy because blood from a developing fetus doesn't mingle with your own until the time of delivery. The immune system of an Rh negative mom has to be exposed to Rh positive blood one or more times before it can develop a response that is strong enough to harm the baby The most common type of blood type incompatibility is Rh disease (also known as Rh incompatibility). The Rh factor is a protein on the covering of red blood cells. If the Rh factor protein is present, the person is Rh positive. If the Rh factor protein isn't present, the person is Rh negative If you're Rh-negative and your baby is Rh-positive, your body will react to the baby's blood as a foreign substance. It will create antibodies (proteins) against the baby's blood. These antibodies usually don't cause problems during a first pregnancy. But Rh incompatibility may cause problems in later pregnancies, if the baby is Rh. Rh- Iso imunization Definition known as: Rhesus incompatibility ,Rhesus disease RhD Hemolytic Disease of the Newborn. -When Rh- mother gets pregnant to Rh+ fetus —she may be sensitized to Rh antigen and develop antibodies. These will cross the placenta and cause hemolysis of fetal red blood cells. 4

Rh Incompatibility In Pregnancy: Causes, Diagnosis and

In contrast to Rh incompatibility, which tends to become more severe with each subsequent Rh positive pregnancy, ABO incompatibility does not demonstrate any consistent pattern. Thus, the patient's first offspring may have clinically important hemolytic disease of the newborn due to ABO incompatibility, while subsequent newborns may be. o Isoimmunization immediately after current pregnancy is 1% and can occur after exposure to <0.1mL of Rh-positive blood. The incidence can be decreased to 0.2% after anti-D administration at 28 weeks or in 12 week intervals. o Brand names of Rh immune globulin: RhoGAM and MICRhoGam (Johnson and Johnson) This condition, generally called Rh disease or Rh incompatibility, occurs during pregnancy when a mother and child carry different Rhesus (Rh) protein factors in the covering of their red blood cells. It occurs when a woman is Rh-negative, and her child is Rh-positive, and can cause the mother's immune system to make Rh antibodies that attack.

Rh sensitization can occur when a person with Rh-negative blood is exposed to Rh-positive blood. During pregnancy, an Rh-negative woman can become sensitized if she is carrying an Rh-positive fetus. Things that increase the risk of blood mixing and sensitization during pregnancy include: Delivery Rh Incompatibility. Mother is Rh (-) and baby is Rh (+). Mother has potential to create anti Rh (+) antibodies. RBC's do not cross the placenta, but IgG antibodies do. There must be a traumatic event when the fetus's blood comes in contact with the mother's blood to trigger antibody production. Uterine trauma. Amniocentesis

Video: Rh incompatibility in pregnancy - Symptoms, Diagnosis

Rh incompatibility: MedlinePlus Medical Encyclopedi

Rh Incompatibility I Hemolytic Disease of the Newborn

Alloimmunization, often called Rh-isoimmunization or Rh incompatibility was first described in Rh negative women with an Rh-positive fetus, but it can occur with many other blood type incompatibilities. It is a condition that may occur during pregnancy when there is an incompatibility between your blood type and your baby's blood type Rh incompatibility results when a pregnant mother with a negative blood type is carrying a child with a positive blood type. This can be a serious risk of health to the unborn child, since the mother's body may react to the child's blood type by producing antibodies against it. Rh incompatibility only occurs when the mother is negative. Who does Rh Incompatibility cause harm to: Mom, Baby, or Both. Etiology: Pregnancy This happens when the Rh- blood is exposed to Rh+ blood the second time (possibly with second pregnancy) The antibodies cross the placenta right away and cause a lot of issues early on. Next steps if Mom is Rh Rh factor is not typically a health concern until pregnancy occurs or a blood transfusion is needed. Rh incompatibility is a mismatch between the blood of the mother and the blood of the fetus and occurs when the mother is Rh negative and the fetus is Rh positive. The FDA approved RhoGAM in 1968, and since then it has saved countless lives

Rhesus disease (Rh disease) is a condition caused by an incompatibility between the blood of a mother and that of her fetus. If the mother is Rh-negative and her baby is Rh-positive, during. Rh incompatibility is the most common cause of the condition, but other factors can also be responsible, including other cell or blood incompatibilities that produce antibodies Rh (rhesus) factor incompatibility is a condition that occurs when a mother is Rh negative (Rh-) and her baby is Rh positive (Rh+). Rh factor is a protein found on red blood cells. You are Rh+ if you have this protein and Rh- if you do not have it. Rh incompatibility usually has little effect on your first pregnancy, but can cause problems with. In Rh incompatibility, maternal IgG antibodies form after maternal exposure to fetal Rh-positive blood during birth or pregnancy-related complications (e.g., fetomaternal hemorrhage). The initial pregnancy is not affected; however, subsequent pregnancies are at risk of fetal hemolysis and, in severe cases, intrauterine hydrops fetalis If you test Rh positive, there is no potential problem of blood incompatibility with the fetus. A pregnant woman's Rh positive blood will not interact with the blood of the fetus in any harmful way. Remember, it's about a potential immune system response; this will not happen if your blood is Rh positive

Rh Incompatibility in Pregnancy NCLEX Revie

Rh factor incompatibility is screened for during pregnancy; an expectant mom can be given a shot to deflect problems. In the past, an HDN (clinically known as erythroblastosis fetalis) could put a baby's health at serious risk Hemolytic disease of the newborn, also known as hemolytic disease of the fetus and newborn, HDN, HDFN, or erythroblastosis foetalis, is an alloimmune condition that develops in a fetus at or around birth, when the IgG molecules (one of the five main types of antibodies) produced by the mother pass through the placenta.Among these antibodies are some which attack antigens on the red blood cells.

Rh Incompatibility | Michigan Birth Injury & HIE AttorneysRh Incompatibility - Complications, Causes, Symptoms, Dx, Rx

Rh Incompatibility - rchsd

Overview. Rh hemolytic disease of the newborn is caused by Rh incompatibility. maternal anti-Rh IgG antibodies cross the placenta and destroy fetal Rh-positive red blood cells. Epidemiology. incidence. 15% of the population is Rh-negative. risk factors. history of prior blood transfusion. previous pregnancy Rh incompatibility is a condition that develops when a pregnant woman has Rh-negative blood and the baby in her womb has Rh-positive blood. Alternative Names. Rh-induced hemolytic disease of the newborn; Erythroblastosis fetalis. Causes. During pregnancy, red blood cells from the unborn baby can cross into the mother's blood through the placenta Pollack W, Ascari WQ, Kochesky RJ, et al. Studies on Rh prophylaxis. 1. Relationship between doses of anti-Rh and size of antigenic stimulus. Transfusion 1971; 11:333. Kumpel BM. On the mechanism of tolerance to the Rh D antigen mediated by passive anti-D (Rh D prophylaxis). Immunol Lett 2002; 82:67 During that pregnancy, the mother's antibodies cross the placenta to fight the Rh positive cells in the baby's body. As the antibodies destroy the red blood cells, the baby can become sick. This is called erythroblastosis fetalis during pregnancy. In the newborn, the condition is called hemolytic disease of the newborn

Sudden Pregnancy Complications: Hydramnios, Rh

Rh incompatibility is actually a medical condition which occurs throughout a woman's pregnancy. A woman's blood type may not have a Rh factor, and her baby's blood type does, so incompatibility occurs. Just like a person's blood type, a person inherits their Rh factor from their parents. Most people have the positive Rh factor, but there are a. Maternal antibodies produced in response to paternally derived D antigens on fetal red blood cells are the leading cause of severe haemolytic disease of the fetus and newborn (erythroblastosis fetalis). Effective immunoprophylaxis of rhesus D-negative at-risk mothers is key to primary prevention... Rh incompatibility refers to the scenario where the mother is Rh negative and the baby is Rh positive. Our bodies are programmed to reject foreign proteins, so if I was going to give someone a blood transfusion, I would make sure the blood is matched up to them, says Victor A. Rosenberg, MD, an ob-gyn and maternal-fetal medicine specialist in private practice in Valley Stream, New York The Rh factor (ie, Rhesus factor) is a red blood cell surface antigen that was named after the monkeys in which it was first discovered. Rh incompatibility, also known as Rh disease, is a condition that occurs when a woman with Rh-negative blood type is exposed to Rh-positive blood cells, leading to the development of Rh antibodies

Rhesus incompatibility in pregnancy: a case report Ali Sungkar1*, Raymond Surya1, Andrew Pratama Kurniawan2 Introduction: Hemolytic disease of the fetus and newborn (HDFN) occurs due to the destruction of red blood cells, which the most common cause is rhesus incompatibility. This study aims to presen The pregnancy will be monitored more closely than usual, as will the baby after delivery. Read more about preventing rhesus disease and diagnosing rhesus disease. Treating rhesus disease. If an unborn baby does develop rhesus disease, treatment depends on how severe it is. A blood transfusion to the unborn baby may be needed in more severe cases While Rh incompatibility rarely causes complications in a first pregnancy, during a subsequent pregnancy the Rh factor can result in severe anemia, jaundice, brain damage, and heart failure in a newborn. To protect against Rh factor problems, you should have a blood test done at an early stage of pregnancy Test. As methods vary between laboratories performing this test, each should report the titer below which severe fetal Rh incompatibility is unlikely (1:16) and above which further investigations and monitoring are indicated. Abdel-Fattah S, Soothill P. Assessing the severity of haemolytic disease of the fetus and newborn: clinical aspects Rh incompatibility is a condition that develops when a pregnant woman has Rh-negative blood and the baby in her womb has Rh-positive blood. Causes During pregnancy, red blood cells from the unborn baby can cross into the mother's blood through the placenta